Comparative effectiveness

Comparative effectiveness evaluates how a treatment performs relative to other available options in terms of efficacy, safety, and real-world outcomes.

What is comparative effectiveness?

Comparative effectiveness refers to the direct or indirect comparison of two or more interventions to determine which one may provide better outcomes for a specific patient population. It may involve head-to-head clinical trials, network meta-analyses, or real-world studies.

Why is comparative effectiveness important in healthcare decision-making?

Comparative data are essential for payer evaluations, HTA reviews, and clinical guideline development. It supports product positioning, helps identify areas of competitive advantage, and informs stakeholder decisions around coverage, prescribing, and resource allocation.

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