# Burden Engine
> A standing burden-of-illness dataset that stays current.
Source: https://www.visfo.health/product/burden-engine
Tags: Live data

_A standing burden-of-illness dataset that stays current._

A managed BOI dataset for your indication, epidemiology, cost, quality-of-life and productivity evidence, refreshed on a cadence so the unmet-need argument never goes stale. One canonical dataset that the Model Studio, GVD, HTA Console and advocacy work all read from.

## What it is

A managed burden-of-illness dataset for the indication, prevalence, incidence, mortality, direct and indirect cost, utilities and productivity loss, segmented by country, line, severity and patient sub-population.

Not a static report. A living dataset, refreshed on a cadence, with provenance to source studies and a change log so every claim a payer, agency or advocate hears can be traced back to a study, a method and a date.

## How we run it

1. **Lock the BOI question, not just the indication** — Per market and per audience, define exactly what burden you must defend: lifetime cost per patient, working-age productivity loss, caregiver hours, mortality gap vs comparator. The dataset is built against those questions, not as a generic dump.

2. **Pull the evidence through ESE** — Searches, screening and extraction run inside the Evidence Synthesis Engine on a cadence. Epidemiology, costing and HRQoL evidence is extracted into a typed schema with source-attribution at the row level.

3. **Reconcile and segment** — Cross-study reconciliation by country, line, severity and sub-population. Conflicting estimates are surfaced with the methodological reason (study design, costing perspective, year, currency) rather than averaged away.

4. **Publish to the spine** — Numbers flow to Model Studio (CE and BIM inputs), GVD (BOI chapter), HTA Console (unmet-need section) and advocacy work. Each downstream surface reads the same number, with the same provenance and the same currency-year.

## What you get

- Live BOI dataset by country, line, severity and sub-population, prevalence, mortality, cost, utility, productivity

- Provenance at the row level, every estimate links back to study, method, year, currency, costing perspective

- Change feed when refreshed, what moved, by how much, and which downstream surfaces need to re-publish

- BOI chapter for the GVD and unmet-need section for the HTA Console, generated from the canonical dataset

- Working-age productivity and caregiver-burden cuts for advocacy and policy conversations